The genetic control of neocortex volume and covariation with neocortical gene expression in mice.

Despite these differences in methodology, there was a highly significant correlation ( r = 0.78, P < .001) between the neocortical volume estimates of Beatty and Laughlin and our own for the 36 strains common to both studies, and the correlation between the regressed cerebral volume estimates – the variable used to map these traits – is also quite high ( r = 0.68, P < .001).

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Effects of sex ( F 1,209 < 1, NS; females = 101.1 ± 1.2 mm 3 ; males = 102.6 ± 1.3 mm 3 ), plane of section ( F 1,209 = 2.1, NS; horizontal = 101.2 ± 1.3 mm 3 ; coronal = 103.5 ± 1.2 mm 3 ), or age ( F 1,209 = < 1, NS) were modest and did not reach statistical significance.

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