Pain Controlling and Cytokine-regulating Effects of Lyprinol, a Lipid Extract of Perna Canaliculus, in a Rat Adjuvant-induced Arthritis Model.

Evid Based Complement Alternat Med · 2009 · PMC2686621 · PMID 18955235

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highly significantno p-value reported

Clinical studies, either controlled or randomized, have demonstrated that Lyprinol® has highly significant AI activity in patients with osteoarthritis (OA) ( 4 , 7 , 8 , 21 ), asthma ( 22 ) and other inflammatory conditions ( 10 ).

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did not reach statistical significanceno p-value reported

IL-10, an ‘anti-inflammatory’ cytokine was increased in the Lyprinol® and in the Naproxen group, but did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.