In the three studies designed to compare outcomes from standard treatment with or without cetuximab [ 22 , 24 , 25 ], patients with KRAS MT tumors showed a decrease in TTP in the cetuximab-containing arm compared with the standard treatment arm, although the difference in each individual study did not reach statistical significance.
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Individualized therapies in colorectal cancer: KRAS as a marker for response to EGFR-targeted therapy.
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