Analysis of host-mediated repair mechanisms after human CNS-stem cell transplantation for spinal cord injury: correlation of engraftment with recovery.

11D ), although the latter demonstrated a strong trend for reduction in astroglial scarring with an increase in hCNS-SCns engraftment. hFb engraftment also did not correlate with the area occupied by the NG2 proteoglycan ( Fig. 12D ) (Pearson r : r = 0.01, p = 0.98, 2-tailed t-test ); as well, no significant correlations between hFb engraftment and GFAP-positive astrogliosis ( Pearson r : r = 0.22, p = 0.63, 2-tailed t-test ) were observed ( Fig. 12D ), but interestingly and again in contrast to hCNS-SCns, there was a strong yet non-significant trend for an increase in astroglial scarring with an increase in hFb number.

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