Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells.

BMC Cancer · 2009 · PMC2693528 · PMID 19473483

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showed a trendno p-value reported

Lapatinib prolonged overall survival and showed a trend towards improved time to progression in a subgroup of patients with tumors that overexpressed the EGF receptor (compared to standard hormone therapy) [ 4 ].

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