Furthermore, the mean duration of seizures at the 125 mg/kg dose showed a strong trend to overall increased seizure duration in the HCl group where the mean duration was ten-fold higher in mice administered bupropion HCl compared to equimolar bupropion HBr.
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Electroencephalographic and behavioral convulsant effects of hydrobromide and hydrochloride salts of bupropion in conscious rodents.
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