Activation of PPARγ by Rosiglitazone does not negatively impact male sex steroid hormones in diabetic rats.

PPAR Res · 2009 · PMC2696180 · PMID 19536350

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The ZDF-untreated rats, however, showed a trend for lower FSH and LH (ZDF-untreated versus lean nondiabetic) and treatment with rosiglitazone reversed this tendency (ZDF-treated versus ZDF-untreated rats) (Figures 6(a) and 6(b) ). 4.

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