Candesartan in heart failure.

Clin Interv Aging · 2006 · PMC2699637 · PMID 18046913

Europe PMC DOI

hedged sentence

0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

did not reach statistical significancep=0.055so close (0.05 < p ≤ 0.1)

In the CHARM-Overall analysis, there was a 9% RRR in all-cause mortality that did not reach statistical significance initially (p=0.055; placebo 25% vs candesartan 23%), but became significant after adjustments for covariates (p=0.032; hazard ratio [HR] 0.9, 95% confidence interval [CI] 0.82–0.99).

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