The role of senescence and prosurvival signaling in controlling the oncogenic activity of FGFR2 mutants associated with cancer and birth defects.

Hum Mol Genet · 2009 · PMC2701333 · PMID 19403560

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did not reach statistical significanceno p-value reported

FGFR2 K569E also provided some protection against c-Myc-dependent apoptosis (that did not reach statistical significance), but strikingly, in the presence of PD173074 , nearly all cells expressing c-Myc and FGFR2 K569E had undergone apoptosis within 14 hours of serum deprivation (Fig. 5 A–C).

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