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A prospective, randomised, placebo-controlled study to identify biomarkers associated with active treatment in psoriatic arthritis: effects of adalimumab treatment on synovial tissue.

Ann Rheum Dis · 2009 · PMC2703703 · PMID 18647851

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Following adalimumab treatment there was also a decrease in the number of CD163-positive cells (resident macrophages) and CD68-positive macrophages, especially in the synovial sublining, but these changes did not reach statistical significance, possibly due to the relatively small number of patients.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.