Following adalimumab treatment there was also a decrease in the number of CD163-positive cells (resident macrophages) and CD68-positive macrophages, especially in the synovial sublining, but these changes did not reach statistical significance, possibly due to the relatively small number of patients.
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A prospective, randomised, placebo-controlled study to identify biomarkers associated with active treatment in psoriatic arthritis: effects of adalimumab treatment on synovial tissue.
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