Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.

Combining the allele scores for all three lipid measures, in a total allele count score that included all 21 risk variants, resulted in an association between combined allele count and MI with an OR of 1.16 (95% CI 1.04–1.30, P = 0.007): all but the LDL risk variant score gave nominally significant P -values (<0.05).

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