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An exploration of the ability of tepoxalin to ameliorate the degradation of articular cartilage in a canine in vitro model.

BMC Vet Res · 2009 · PMC2719625 · PMID 19624842

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showed a trendno p-value reported
PGE 2 concentration in culture media at day 7 was significantly increased by IL-1 β and OSM and treatment with both tepoxalin and its metabolite showed a trend towards dose-dependent reduction of PGE 2 production.

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