beta1 integrin maintains integrity of the embryonic neocortical stem cell niche.

Interestingly, in keeping with the rostro-caudal differences in β1 integrin blockade described in Figure 3 spatial discrepancies were also found in the postnatal cortex of animals injected with β1 integrin blocking antibody at E15.5; cortical layer thickness was reduced in somato-sensory but not in the primary motor cortex, although these results did not reach statistical significance.

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