There was a 35% improvement in urge incontinence, 30% improvement in pain and a 20% improvement in incontinence-related quality of life.[ 32 ] Another study confirmed an apparent benefit of PTNS, but showed a diminished rate of success if instability symptoms were severe.[ 33 ] A recent study of PTNS in combination with low-dose oxybutynin for refractory OAB had an 83.2% response rate compared to 61.6% in the PTNS only group.[ 34 ] Although the differences did not reach statistical significance, this small study suggests a possible role of combination therapy to improve the efficacy of PTNS alone.
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