GSTM1 and GSTP1 polymorphisms as potential factors for modifying the effect of smoking on inflammatory response.

J Korean Med Sci · 2006 · PMC2721922 · PMID 17179680

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

did not reach statistical significancep =0.08so close (0.05 < p ≤ 0.1)

Obesity was found to be significantly associated with increase of WBC count ( p <0.01), but the observed increase of TNF-α with obesity did not reach statistical significance ( p =0.08).

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marginally significantno p-value reported

However, when we analyzed the effect of smoking on TNF-α level according to genotype combination, smoking showed marginally significant effect on TNF-α level in subjects with combination of GSTM1 null and GSTP1 AG or GG genotypes in spite of low level of tobacco smoke exposure.

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borderline significanceno p-value reported

In addition, our study showed borderline significance of smoking on TNF-α level, probably due to small sample size.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.