As expected, the expression profile of cases defining the MCR of gain at 7p11.2 demonstrated highly significant over-expression of EGFR .
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An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors.
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The sentences
A similar analysis of the 12p12 MCR and KRAS mutation status demonstrated a trend for cases defining the MCR to harbor a KRAS mutation, but this did not reach statistical significance (not shown).