Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.

P < 0.05 was considered nominally significant, and P < 6.9 × 10 −4 calculated using Bonferroni correction for multiple comparisons was considered statistically significant, given 72 independent tests for 18 SNPs and four outcomes measured (obesity [BMI], insulin release [InsAUC 0–30 /GluAUC 0–30 ], insulin sensitivity [Matsuda ISI], and proinsulin conversion [ProinsAUC 0–30 /InsAUC 0–30 ]).

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