There was a significant trend for increasing duration of disease and lower percentage of total brain volume ( P trend < 0.001), lower percentage of gray matter ( P trend < 0.001) and white matter ( P trend < 0.001), and higher percentage of WMLs ( P trend = 0.05) ( Table 3 ).
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Glycemic status and brain injury in older individuals: the age gene/environment susceptibility-Reykjavik study.
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