Reduced Fas ligand-expressing splenic CD5+ B lymphocytes in severe collagen-induced arthritis.

Analysis of splenic lymphocyte populations from individual mice showed that the total number of white cells ranged from 5.5 × 10 7 to 1.7 × 10 8 cells per mouse, with a trend (that did not reach statistical significance) toward fewer total lymphocytes in the more severely arthritic mice (Table 1 ).

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