The immunobiology of primary sclerosing cholangitis.

While the male to female predominance of 2:1 for PSC has been largely reported, a study from Turkey reported that 15/16 PSC patients in their series were women [ 13 ] and a Canadian study reported a slight male predominance that did not reach statistical significance, with an age-adjusted incidence rate of 1.01 per 100,000 person-years for men versus 0.84 per 100,000 person-years for women [ 8 ].

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