Conformationally rigid nucleoside probes help understand the role of sugar pucker and nucleobase orientation in the thrombin-binding aptamer.

Nucleic Acids Res · 2009 · PMC2761269 · PMID 19620215

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hedged sentence

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closest p

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boldest claim

The sentences

quite significantno p-value reported

In both cases, the difference found was quite significant (3–4 kcal/mol) indicating that the population of the minor conformer in solution would be negligible ( Table 1 ).

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