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Glucocorticoids can activate the alpha-ENaC gene promoter independently of SGK1.

Biochem J · 2009 · PMC2762689 · PMID 19619128

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However, these apparent effects did not reach statistical significance (one-way ANOVA), and so neither construct has any direct effect upon the transcriptional activity of the promoter region of the α-ENaC gene.

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