Confirmation of genetic associations at ELMO1 in the GoKinD collection supports its role as a susceptibility gene in diabetic nephropathy.

Diabetes · 2009 · PMC2768169 · PMID 19651817

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nominally significantno p-value reported

Because recent studies have suggested that the development of proteinuria and its progression to ESRD may be influenced by different genetic factors, we analyzed the eight nominally significant ELMO1 SNPs for association with prevalent proteinuria ( n = 284) and ESRD ( n = 536) ( Table 2 ) ( 20 , 21 ).

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