CpG-depleted promoters harbor tissue-specific transcription factor binding signals--implications for motif overrepresentation analyses.

As expected, over all tissues there is a clear trend for the most tissue-specific genes to fall into the class of CpG-depleted promoters.

also in 19,460 other papers

As shown in Supplementary Figures S5 and S6 , we find a weak trend for the general TFs and core promoter motifs to occur preferentially in CpG-rich promoters.

also in 1,404 other papers