a clear trendP > 0.70
In contrast, DRB1*0802 (Table S2) as another common allele in the DRB1*08 group did not show a clear trend for positive or negative association ( n = 16, β = 0.18 ± 0.48, P > 0.70), neither did the less frequent allele DRB1*0801 ( n = 9, β = 0.74 ± 0.64, P = 0.249).