Investigation of the association between CALCRL polymorphisms and primary angle closure glaucoma.

Single marker analysis Allele and genotype frequency comparisons between APACG patients and controls demonstrated nominally significant differences with p values of 0.024 and 0.028, respectively, for the C/T polymorphism at intron 1 ( rs1157699 ), but this significance was lost after Bonferroni correction (corrected p value 0.144 and 0.168, respectively).

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The results show rs1157699 is nominally associated with APACG with a marginal significance (uncorrected p value 0.024 and 0.028 observed in allele and genotype analyses, respectively, of this site).

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