Evidence for a lack of a direct transcriptional suppression of the iron regulatory peptide hepcidin by hypoxia-inducible factors.

PLoS One · 2009 · PMC2773926 · PMID 19924283

Europe PMC DOI

hedged sentence

0.0560

closest p · 1.1× alpha

0.0560

boldest claim

The sentences

did not reach statistical significancep = 0.056so close (0.05 < p ≤ 0.1)

The induction by IL-6 may have been attenuated in HepG2 cells in the presence of DMOG, although this difference did not reach statistical significance (IL-6 2.7±0.9-fold, IL-6 plus DMOG 1.23±0.2-fold vs. unstimulated controls; n = 3, p = 0.056; Figure 5C ).

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