( 2006 ) discovered a statistically significant increase in the expression of DAAO-mRNA in the cerebellum of schizophrenic patients, but their immunohistochemical studies only showed a trend of the protein level in this direction.
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Increased D-amino acid oxidase expression in the bilateral hippocampal CA4 of schizophrenic patients: a post-mortem study.
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Another meta-analysis on DAOA by Detera-Wadleigh and McMahon ( 2006 ) presented highly significant evidence of an association between nucleotide variations in the DAOA/DAAO region and schizophrenia.