The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake.

Nat Med · 2009 · PMC2777744 · PMID 19767734

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showed a trendno p-value reported

Notably, in the basal state Pomc–Foxo1 −/− mice showed a trend toward increased serum ghrelin that also mimics CR ( Supplementary Fig. 7c ) 38 .

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