AIRE activated tissue specific genes have histone modifications associated with inactive chromatin.

Hum Mol Genet · 2009 · PMC2778368 · PMID 19744957

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a clear trendno p-value reported

As can be seen in Supplementary Material, Figure S7A and B , we observed a clear trend for genes with high expression levels to have H3K4me3 and AcH3 marks at their promoter regions.

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