Predicting risk of osteoporotic fracture in men and women in England and Wales: prospective derivation and validation of QFractureScores.

There was a borderline significant decrease in risk (0.01<P<0.05) with low dose unopposed equine oestrogen, low dose unopposed non-equine oestrogen, high dose unopposed non-equine oestrogen, and continuous high dose non-equine.

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For consistency, we also included current use of corticosteroids in the final models for osteoporotic fracture and hip fracture, although it tended towards significance only for hip fracture (P=0.067), which might reflect the lower numbers of patients with a hip fracture.

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