Chemerin is a novel adipocyte-derived factor inducing insulin resistance in primary human skeletal muscle cells.

Diabetes · 2009 · PMC2780878 · PMID 19720798

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showed a trendno p-value reported

This effect was dose dependent because administration with 250 ng/ml of chemerin showed a trend toward induction of insulin resistance, whereas 1 μg/ml of chemerin provoked a significant decrease in insulin-stimulated phosphorylation of Akt and GSK3α/β.

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