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Endoplasmic reticulum stress in diabetic hearts abolishes erythropoietin-induced myocardial protection by impairment of phospho-glycogen synthase kinase-3beta-mediated suppression of mitochondrial permeability transition.

Diabetes · 2009 · PMC2780889 · PMID 19755525

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GSK-3β level in total myocardial homogenates in OLETF rats was 25% higher than that in LETO rats, though this difference did not reach statistical significance ( Fig. 4 A ).

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