RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.

The remaining six SNPs did not reach statistical significance in the SICS but did exhibit consistent associations in terms of odds ratios and allele frequencies and combining data from the NECS and SICS made these ten associations even stronger plus an additional three other SNPs became statistically significant.

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The SNP rs1533484 was borderline significant (Bayesian significance ∼0.06) and demonstrates consistent effects with the NECS and SICS results, but the allele frequencies are substantially different.

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