Protective versus pathogenic anti-CD4 immunity: insights from the study of natural resistance to HIV infection.

J Transl Med · 2009 · PMC2789051 · PMID 19943950

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failed to reach statistical significanceno p-value reported

Recently, a fully human anti-CD4 monoclonal antibody (HuMax-CD4) was tested in a multicenter, double blind, placebo-controlled, randomized clinical trial on 85 moderate to severe psoriasis patients, showing decreases in the psoriasis skin score, although this failed to reach statistical significance [ 41 ].

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