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Beclin-1 expression is a predictor of clinical outcome in patients with esophageal squamous cell carcinoma and correlated to hypoxia-inducible factor (HIF)-1alpha expression.

Pathol Oncol Res · 2009 · PMC2791489 · PMID 19130303

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There was a tendency for shorter survival in patients with high HIF-1α expression, but this correlation did not reach statistical significance, probably owing to short periods of follow-up and the small number of patients enrolled in our study.

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