Barely Significant
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Extraordinary molecular evolution in the PRDM9 fertility gene.

PLoS One · 2009 · PMC2794550 · PMID 20041164

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highly significantP<0.0001actually significant
In the entire PRDM9 protein of 894 amino acids, only 96 amino acids are in a DNA-binding turn-helix region (8 in each of 12 ZF domains), indicating a highly significant enrichment of nonsynonymous SNPs in turn-helix residues (24/31 vs. 96/894, P<0.0001 by Fisher's exact test).

also in 132,142 other papers

Several additional codons in DNA-binding turn-helix regions also had high estimated d N /d S values that did not reach statistical significance.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.