Zinc transporter 8 antibodies complement GAD and IA-2 antibodies in the identification and characterization of adult-onset autoimmune diabetes: Non Insulin Requiring Autoimmune Diabetes (NIRAD) 4.

The clinical phenotype analyzed according to the number of islet autoantibodies showed a trend toward a younger age at diagnosis, more prominent features of insulin deficiency (higher fasting glucose and A1C and lower BMI, waist circumference, total cholesterol, triglycerides, and uric acid), and higher prevalence of associated TPO antibodies proportional to the number of autoantibodies (all P trend < 0.001).

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