Detection of R576 interleukin-4 receptor an allele gene, serum interleukin-4, and eosinophilic cationic protein in atopic dermatitis patients.

There was a highly significant increase in the total IgE, eosinophil count, and ECP levels in homozygous R576/R576 atopic patients ( P < 0.001).

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Rogala et al, [ 23 ] hypothesized that there is strong evidence that the R576 allele might predispose to atopy in a Polish population, but their results did not reach statistical significance.

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