Additional analyses were carried out on four variants that showed a trend for association ( PALB2 c.1592delT, 1674A>G, 2993G>A and 3300T>G).
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PALB2 variants in hereditary and unselected Finnish prostate cancer cases.
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We found that the 2993G>A variant exhibits a borderline significant odds ratios in a subgroup of 380 unselected cases with a Gleason score over seven and an age at diagnosis less than 61 years (20/380; OR 1.9; 95% CI 1.0-3.5).