After ileitis induction, RAG1 −/− mice displayed lower IL-22 concentrations in the ileum compared with WT mice, but this difference did not reach statistical significance ( Fig. 6 B ).
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Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.
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