A possible link between possible changes of the RAAS and the HPA system in depression was further demonstrated by the significant increase in aldosterone secretion after administration of the glucocorticoid receptor agonist dexamethasone in healthy female subjects, whereas in depressed females aldosterone showed a trend to a decrease [ 32 ].
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The renin-angiotensin-aldosterone system in patients with depression compared to controls--a sleep endocrine study.
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