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Molecular footprints of a germinal center derivation of human IgM+(IgD+)CD27+ B cells and the dynamics of memory B cell generation.

J Exp Med · 2009 · PMC2806629 · PMID 19917772

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The fact that the intrinsic SHM biases analyzed did not reach statistical significance in all instances might be caused by the restricted number of mutation events analyzed and/or by the fact that some Bcl6 mutations influence Bcl6 expression ( Pasqualucci et al., 2003 ) and hence may be selected for or against.

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