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An autoinhibitory tyrosine motif in the cell-cycle-regulated Nek7 kinase is released through binding of Nek9.

Mol Cell · 2009 · PMC2807034 · PMID 19941817

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a clear trendno p-value reported
The series of mutants we made in Nek7 show a clear trend in activity and thus provide some illumination on the first point.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.