Irritability in pre-clinical Huntington's disease.

A significant interaction with gene status was found in left amygdala and a strong trend in right amygdala resulted from PSCs failing to show the expected positive correlation with negative feedback ( T = 4.02; p = 0.005; at x , y , z = −18, −6, −12 and T = 3.37; p = 0.06 at x , y , z = 18, −8, −14; Fig. 2 ).

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