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Genetic analysis of typical wet-type age-related macular degeneration and polypoidal choroidal vasculopathy in Japanese population.

J Ocul Biol Dis Infor · 2009 · PMC2816809 · PMID 20157352

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The heterozygous (CA) risk genotype of rs10490924 was detected more often in PCV cases than in controls with p value of 0.0008 and OR of 2.8 (95% CI = 1.5–5.2), however the difference in the frequency of the heterozygous (CA) at the same loci between typical wet-type AMD cases and controls did not reach statistical significance.

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