Correlating lesion size and location to deficits after ischemic stroke: the influence of accounting for altered peri-necrotic tissue and incidental silent infarcts.

Statistical analysis of motor impairment measure and lesion volumes As indicated in Table 2 , the mean volume of the lesion core (Region 1) alone was significantly correlated to FM scores (r = -0.35, p = 0.025), and the volume of the peri-necrotic tissue showed a weak trend toward significant association with FM scores (Region 2; r = -0.26, p = 0.10).

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The association between motor impairment scores and the mean volume of lacunes did not reach statistical significance (r = 0.029, p = 0.86), nor did the association between motor impairment scores and the mean volume of lesions in the opposite hemisphere (r = 0.005, p = 0.98).

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