Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.

Nat Genet · 2010 · PMC2828525 · PMID 20154673

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highly significantno p-value reported

In addition to the 7p21 locus, analysis of the GRN cases alone showed highly significant association with SNPs near the GRN locus on 17q21 ( Fig. 3 and Supplementary Table 7 ).

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showed a trendno p-value reported

In addition to the 7p21 locus, the GWAS of GRN negative cases showed a trend for association at five other loci ( Supplementary Table 8 ) including a locus on chromosome 9p21.2 that falls within a 7.7 Mb critical interval defined from five previous linkage studies, representing a potential refinement of that region 26 .

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