Restoration of muscle mitochondrial function and metabolic flexibility in type 2 diabetes by exercise training is paralleled by increased myocellular fat storage and improved insulin sensitivity.

Training induced a modest but near-significant decline in body weight and BMI in control subjects (94.7 ± 2.7 to 93.6 ± 2.7 kg and 29.7 ± 0.8 to 29.4 ± 0.8 kg/m 2 , respectively, both P = 0.06), but did not result in significant changes in type 2 diabetic subjects ( Table 1 ).

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