Antibody titers were higher in hACE2 Tg mice immunized with rSARS-CoV-ΔE when compared to rSARS-CoV-Δ[E,6-9b]-immunized animal, although these differences did not reach statistical significance ( p = 0.16).
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Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease.
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0.1600
0.1600